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Bioresources:
The
Bioresources area focuses on living organisms and their
applicability to Biopharmaceuticals. There are six research
teams under this area of activity and encompasses marine,
freshwater and terrestrial phototrophs , heterotrophs
and large plants.
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The
Phototroph Research Group:
The
Phototroph Research Group works on a number of marine
and fresh water algae and cyanobacteria for the production
of various target biochemicals. This Group also works
developing protocols for the commercial scale production
of various cultures as well as optimal stimulus for
production of targeted biochemicals.
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The
Heterotroph Research Group:
The
Heterotroph Research Group focuses on fungi and bacteria
from marine, mangrove as well as terrestrial sources
for the production of biopharmaceuticals and enzymes.
This group has done commendable work on Omega Fatty
Acids and phytopharmaceuticals.
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The
Heterotroph Germ Plasm Group
The
Heterotroph Germ Plasm Group concentrates on culture
collection, purification and viable maintenance of wild
strains of fungi and bacteria from remote and extreme
environments. Researchers trawl different environments
including the deep sea, mangroves and mountain environments
for new strains of fungi and bacteria with relevant
applications. This heterotroph Germ Plasm Group manages
over 1500 strains in its culture collection.
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The
Phototroph Germ Plasm Group
The
Phototroph Germ Plasm Group focuses on algae and cyanobacteria.
Apart from over 500 useful strains, this group also
works on predator control of various organisms which
impede culture of the target organism. This group concentrates
on culture collection, purification and viable maintenance
of wild strains of algae and cyanobacteria from remote
and extreme environments. The group also interfaces
with the National Facility for Marine Cyanobacteria
for continuing enhancement of its culture collection.
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The
Ethnobotany Group
The
Ethnobotany Group works with large organism formats
based on traditional and shamanistic sources of phytopharmaceutical
data. It focuses at phytopharmaceutical leads for various
disease states and works with the Micropropogation as
well as Chemistry Groups in addressing solutions to
both biomass availability as well as creating chemical
analogs in case natural sourcing is difficult. The Ethnobotany
Group also maintains a germ plasm collection of various
types and species of targeted plants so as to have as
wide a selection as possible.
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The
Micropropogation and Cell Culture Group
This
group focuses at creating methodologies for sufficient
biomass production of targeted large plants. It addresses
herbs through micropropagation and induction of nutrient
stresses for production of targeted levels of biochemicals.
It also works on various cell culture models for controlled
production of biomass of plant organisms that have less
cultivation viability.
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Chemistry:
The
Chemistry Lab works on two strategic areas namely Synthesis
and Bioprocess Development. The Synthesis Team works
on synthesis, analog development and biotransformations.
The
Bioprocess Development Group works on upscaling both
biomass production as well as down-stream
processes for extraction and purification of targeted
biochemicals.
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Clinical
Biology:
The
Clinical Biology Area focuses at nine different disease
states and works on screening fractions of various phytochemical
extracts against the following states:
Kidney
disorders, Allergy and skin diseases, Geriatrics, Post
menopausal Syndromes, Arthritis and connective tissue
disorders, Diabetes, Fungal Infections, Oncogenesis
and Viral infections.
This Group also interfaces with the Madras Universitys
Dr.A.L.M. Post Graduate Institute of Basic Medical Sciences
in seeking to develop New Chemical Entities, conduct
invitro and invivo studies on cell and animal models
and offer these to industry
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Special
Projects:
The
Special Projects Group works on the development of platform
technologies in the areas of molecular biology based
plant production models, modulating biosynthetic pathways
and establishing micro-array based screening models.
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